Information Section: Conditions
Condition:
Tourette's Syndrome
Article: Research Studies Seeking Participants

Page 1 of 1

PREFACE

 Studies listed below are attempting to recruit participants and have submitted copies of their Institutional Review Board approval to this web site. If you are interested in participating in a study listed below, please follow the link to the investigator's web site. The studies listed below have no affiliation with this web site's owner or author, and are merely presented here as a courtesy to help participants and researchers find each other.

STUDIES

Columbia University Neuroimaging Study Seeking Participants with Tourette Syndrome

Conducted by Dr. Bradley Peterson, this new research study is focused on learning more about the causes of several disorders that develop in childhood and adolescence. One of the conditions of interest is Tourette Syndrome.

The study requires participants to agree to five visits, one per year over a five year period, and includes multiple MRI scans which lasts about one and a half hours each. Each study visit requires a total of 6-7 hours to complete.

Participants must be between the ages of 4-13, can be taking medications, and also may have other diagnosed conditions in addition to TS.

No expense will be incurred by eligible subjects, and a modest payment for participation is being offered. Participants will receive $120 after each visit, in the form of a gift certificate or a check depending upon age, as a thank you for being in the study. Participants that turn 15 years old during the study will receive $200 for each subsequent visit.

Study location: NY State Psychiatric Institute, Columbia University, New York, NY
Contact person: Kristin Klahr: 1-212-543-6072 <mristudy@childpsych.columbia.edu>

Note: Those contacting the study coordinator to learn more about the project are under no obligation to agree to participate.

Neuroimaging Study:  Adults with TS

The investigators at the Yale Child Study Center are currently looking for adults with TS, or adults who had tics during childhood but are now experiencing much fewer tic symptoms, to participate in these studies. The MEG portion is being conducted at New York University while the fMRI portion of the study is being conducted at the Yale Child Study Center. See the recruitment notice (pdf) for additional information.

fMRI of Motor Tics, Motor Response Preparation and Response Inhibition in Children with TS

Investigators: Stewart Mostofsky, M.D., Principal Investigator; Harvey Singer, M.D., Co-Investigator

Description: The purpose of this study is to use functional magnetic resonance imaging (fMRI) to identify brain regions involved in tic production in children between the ages of 8-18 years. This study is being funded by the Tourette Syndrome Association. Participation in this study involves paper and pencil tasks, computer activities and Magnetic Resonance Imaging (MRI) of the brain. There are no medical benefits and none of the tests are harmful or painful. The study involves two, 5-hour sessions conducted on separate days. Participants will receive a $50 check and a picture of their brain. Parents will receive a copy of their child's IQ report. All testing is done free of charge.

Eligibility:

  • Children with and without Tourette Syndrome
  • Ages 8-18 years
  • Presence of simple tics with minimal head movement (in children with TS)
  • Right handed

Location: Kennedy Krieger Institute, 707 N. Broadway, Baltimore, MD 21205. Contact: Megan Roeder (443) 923-9254 roeder@kennedykrieger.org

Behavior Therapy for Adults and Adolescents with Chronic Tic Disorders

Yale Child Study Center is recruiting subjects for a study of behavior therapy for tics. The purpose of this study is to evaluate whether a form of behavior therapy called Comprehensive Behavioral Intervention for Tics (CBIT) is helpful for reducing tics. CBIT will be compared to Psychoeducational Supportive therapy (PST) and participants of this study will be randomly assigned (like the flip of a coin) to receive CBIT or PST.

Comprehensive Behavioral Intervention for Tics (CBIT) therapy consists of eight one-hour long treatment sessions scheduled over ten weeks. During this treatment, participants with learn to monitor their tics and will practice simple behavioral response that may make the tics less frequent or bothersome. For example, someone who has a leg movement tic, may be asked to practice placing the feet flat on floor and pushing downward. Psychoeducational supportive therapy (PST) will also consist of eight one-hour long sessions scheduled over ten weeks. This treatment involves stress management, problem-solving, and learning strategies for coping with negative emotions.

To be eligible for the study participants must

  • be 16 years of age or older
  • have Tourette Syndrome or Chronic Tic Disorder
  • be medication free or on a stable dose of medication
  • All adults or adolescents and their parents who are involved in the study will be asked to fill out rating scales, questionnaires, and answer questions about symptoms and behavior relevant to this project. CBIT and PST are free. Subjects will be offered $25 each assessment visit, and compensated for parking costs on therapy visits. Participation in this study is voluntary. If you do not want to participate, it will not affect any future treatment in the Yale Child Study Center.

    If you are interested in the project, please contact Dr. Denis Sukhodolsky at (203) 785-6446 or Joseph McGuire at (203) 785-5805. We will describe the project in more detail and help you determine whether the program is fitting for you.

    Information Section: Conditions
    Condition:
    Tourette's Syndrome
    Article: Research Studies Seeking Participants

    Page 1 of 1

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